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Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

C14 epoxide-modified poly(amido amine) dendrimer generation 0

C16 epoxide-modified poly(amido amine) dendrimer generation 2 C14 epoxide-modified PAMAM dendrimer G0 C16 epoxide-modified PAMAM dendrimer G2 PG0.C14 PG2.C16
Type Complex Compound
Formula
Role core
2

small interfering ribonucleic acid

Tie2 siRNA
Type Biomolecule
Formula
Role loaded material
3

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
bEnd.3 endothelial cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • C14 epoxide-modified poly(amido amine) dendrimer generation 0
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. DR6xG0ciaLBI8jQ964BCsjCfSc
Product

Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • C16 epoxide-modified poly(amido amine) dendrimer generation 2
  1. e4Y31rqLDzszzD6kkFZt0gEw76
Product

Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • C12 epoxide-modified poly(amido amine) dendrimer generation 1
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. U6NiTsLlYyGaMWJu7eR5iitfbp
Product

Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • C16 epoxide-modified poly(amido amine) dendrimer generation 1
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. SVtdwMoOOm2FVYldkwBO0ZuLfb
Product

Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  • C14 epoxide-modified generation 1 poly(propylenimine) dendrimer
  1. bnxPhmmgeaAnleEZZgQkaj3c26
Product

Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Size: not specified

Medium/Support: none

References

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