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Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

C16 epoxide-modified generation 1 poly(propylenimine) dendrimer

C16 epoxide-modified PPI dendrimer G1 DG1.C16
Type Complex Compound
Formula
Role core
2

small interfering ribonucleic acid

Tie2 siRNA
Type Biomolecule
Formula
Role loaded material
3

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
colloidal stability

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
bEnd.3 endothelial cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • C16 epoxide-modified generation 1 poly(propylenimine) dendrimer
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. XUIjra2F3dcFb37FCNFyxWX0BM
Product

Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • C16 epoxide-modified generation 1 poly(propylenimine) dendrimer
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. xnap3qQ5jkbjyx0AnY3sNKQWYC
Product

Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • small interfering ribonucleic acid
  • C16 epoxide-modified generation 1 poly(propylenimine) dendrimer
  • 1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
  1. OBjY7hgYWCXPywCD1416gUigLJ
Product

Tie2 siRNA-loaded DG1.C16/1,2-dimyristoyl-sn-glycero-3-phosphoethanolamine-N-mPEG2000 nanoparticles

References

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