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etoposide N-methyl-piperazinyl butanoic acid ester-loaded distearoyl phosphatidylcholine/cholesterol liposomal nanoparticles

Based on

1 Patents
2012 Most recent source

Composition

1

etoposide N-methyl-piperazinyl butanoic acid ester water solution

Type Complex Compound
Formula
Role core
2

hydrogenated soybean phosphatidylcholine

hydrogenated soybean phosphatidylcholine hydrogenated soya phosphatidylcholine hydrogenated soy phosphatidylcholine distearoyl phosphatidylcholine distearoylphosphatidylcholine disteroylphosphatidyl choline L-α-phosphatidylcholine Phospholipon® 80H Soy PC DSPC HSPC SPC
Type Single Compound
Formula C44H88NO8P
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role layer
4

hydrogenated soybean phosphatidylcholine

hydrogenated soybean phosphatidylcholine hydrogenated soya phosphatidylcholine hydrogenated soy phosphatidylcholine distearoyl phosphatidylcholine distearoylphosphatidylcholine disteroylphosphatidyl choline L-α-phosphatidylcholine Phospholipon® 80H Soy PC DSPC HSPC SPC
Type Single Compound
Formula C44H88NO8P
Role layer

Properties

General physical and chemical properties

Property Value Source
drug-loading efficiency

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Applications

Characterization

Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 4-(4-methylpiperazin-1-yl) butanoic acid dihydrochloride salt
  1. laGAvbwoFmqYeuh2
  2. O2jJXE3kDv7nrTVk
Product

etoposide N-methyl-piperazinyl butanoic acid ester-loaded distearoyl phosphatidylcholine/cholesterol liposomal nanoparticles

References

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