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α-tocopherol-based antioxidant-antineoplastic nanospheres

Based on

1 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

D-alpha tocopherol

alpha tocopherol alpha-tocopherol D-α-tocopherol Covitol F1370 α-Tocopherol α-tocopherol tocopherol vitamin E aToc αTOC αToc α-T VE
Type Single Compound
Formula C29H50O2
Role raw materials
2

camptothecin/camptothecin analog derivative

compound C-10 CPT-TEG-ALA
Type Single Compound
Formula C37H44N2O11S2
Role loaded material

Properties

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
female athymic nu/nu mouse with U87 MG glioma xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • camptothecin/camptothecin analog derivative
  • D-alpha tocopherol
  1. ElWCXMJPQZehI1ZgfHyRdUcH9rqficPRM0nBJdVqi
Product

α-tocopherol-based antioxidant-antineoplastic nanospheres

Size: 83 - 173 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • camptothecin/camptothecin analog derivative
  • D-alpha tocopherol
  1. MvfmTzDq3arrjarvYAf9F4muZFAU4FLFg03zV17t5
Product

α-tocopherol-based antioxidant-antineoplastic nanospheres

Size: 147 nm

Medium: water

Support: none

References

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