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RGD/DNA/8-Ad-PAMAM/CD-PEI/Ad-PEG nanoparticles

Based on

1 Patents
2010 Most recent source

Composition

1

adamantane-grafted 1st-generation1,4-diaminobutane core polyamidoamine dendrimer

adamantanamine-grafted polyamidoamine dendrimer octa-Ad-grafted polyamidoamine dendrimer adamantane-grafted PAMAM 8-Ad-PAMAM Ad-PAMAM
Type Single Compound
Formula C152H252N34O20
Role core
2

branched polyetyleneamine

CD-PEI
Type Polymer
Formula
Role core
3

Ad-PEG

Type Polymer
Formula
Role layer
4

CMV-driven enhanced green fluorescent protein (EGFP)-encoded plasmid DNA

CMV-driven EGFP-encoded plasmid DNA
Type Biomolecule
Formula
Role fillers
5

RGD-PEG-Ad

RGD-PEG-Ad
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
α<sub>ν</sub>β<sub>3</sub> 3T3 cels

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • 1-adamantanamine hydrochloride
  • N-hydroxysuccinimide (SCM) and maleimido (MAL) hetero-functionalized polyethylene glycol
  1. GI2FGwyH2N1pLA8FxyP4QhLna
  2. 3E5AyL6VxEaYa
Product

RGD/DNA/8-Ad-PAMAM/CD-PEI/Ad-PEG nanoparticles

Diameter: 100 - 300 nm

Medium/Support: none

References

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