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topotecan-loaded 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy-poly(ethylene glycol)2000] liposomes

Based on

1 Articles
2015 Most recent source

Composition

1

ammonium sulfate aqueous solution

Type Complex Compound
Formula
Role core
2

mixture of substance based on ([(2R)-3-hexadecanoyloxy-2-[(Z)-octadec-9-enoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy-poly(ethylene glycol)2000])

Type Complex Compound
Formula
Role layer
3

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material
4

topotecan hydrochloride

hycamtin
Type Single Compound
Formula C23H23N3O5*HCl
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
cryo-electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
SD rat plasma

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Preparation

Method 1

Type: Physical formation
Source:
  1. fiFqrwu6IwJ5ig7Xux1Xf
  2. DZqRrO
  3. fzDsQZMT
  4. cUc
Product

topotecan-loaded 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy-poly(ethylene glycol)2000] liposomes

Diameter: ~ 70 - ~ 85 nm

Hydrodynamic diameter: ~ 162 nm

Medium/Support: none

References

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