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Pluronic P123-conjugated polypropylenimine dendrimer/pDNA encoding pEGFP-N2 nanocomplex

Based on

2 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Pluronic P123-conjugated polypropylenimine (PPI) dendrimer

P123-PPI
Type Polymer
Formula
Role carriers
2

plasmid DNA

pDNA
Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
genetic engineering

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse bearing MCF-7/ADR tumor

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • Pluronic P123-conjugated polypropylenimine (PPI) dendrimer
  • water
  • plasmid DNA
Product

Pluronic P123-conjugated polypropylenimine dendrimer/pDNA encoding pEGFP-N2 nanocomplex

Hydrodynamic size: ~ 470 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. hKM7bpGonhTpm8EoGTKBm6DRD
Product

Pluronic P123-conjugated polypropylenimine dendrimer/pDNA encoding pEGFP-N2 nanocomplex

Size: not specified

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • Pluronic P123-conjugated polypropylenimine (PPI) dendrimer
  • water
  • plasmid DNA
Product

Pluronic P123-conjugated polypropylenimine dendrimer/pDNA encoding pEGFP-N2 nanocomplex

Hydrodynamic size: ~ 190 nm

Medium: water

Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • Pluronic P123-conjugated polypropylenimine (PPI) dendrimer
  • water
  • plasmid DNA
Product

Pluronic P123-conjugated polypropylenimine dendrimer/pDNA encoding pEGFP-N2 nanocomplex

Hydrodynamic size: ~ 330 nm

Medium: water

Support: none

Method 5

Type: Chemical synthesis
Source:
Starting materials
  • Pluronic P123-conjugated polypropylenimine (PPI) dendrimer
  • water
  • plasmid DNA
Product

Pluronic P123-conjugated polypropylenimine dendrimer/pDNA encoding pEGFP-N2 nanocomplex

Hydrodynamic size: ~ 220 nm

Medium: water

Support: none

References

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