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Hypoxia-inducible factor 1 small interfering RNA-loaded EPL-modified co-polymer nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

methylated polyethylene glycol-b-poly lactic-glycolic acid

mPEG-PLGA
Type Polymer
Formula
Role core
2

ε-polylysine

EPL
Type Biomolecule
Formula
Role layer
3

Hypoxia-inducible factor 1 small interfering RNA

HIF1α-siRNA
Type Biomolecule
Formula
Role layer

Properties

Applications

Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
human pancreatic cancer panc-1

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl) oxolan-2-yl]-1,2-dihydropyrimidin-2-one)
  • methylated polyethylene glycol-b-poly lactic-glycolic acid
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  2. pfd5o
  3. IYvb37YVjn
Product

Hypoxia-inducible factor 1 small interfering RNA-loaded EPL-modified co-polymer nanoparticles

Size: not specified

Medium: fetal bovine serum

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • methylated polyethylene glycol-b-poly lactic-glycolic acid
  1. Lhf9QKdM1JI4NK2w9C
  2. AU8We
  3. 1dVNgjzVy0
Product

Hypoxia-inducible factor 1 small interfering RNA-loaded EPL-modified co-polymer nanoparticles

Size: not specified

Medium: phosphate buffer

Support: none

References

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