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PEI-PDHA/PEG-PDHA/PTX/siSna/siTwi

Based on

1 Articles
2015 Most recent source

Composition

1

HEPES buffer

Type Complex Compound
Formula
Role core
2

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role fillers
3

PEI-PDHA/PEG-PDHA mixture

Type Complex Compound
Formula
Role layer
4

Snail small interfering RNA

Snail siRNA siSna
Type Biomolecule
Formula
Role layer
5

Twist small interfering RNA

Twist siRNA siTwi
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
colloidal stability

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
female BALB/c nude mouse with mouse breast tumor 4T1

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. 9WMZ
Product

PEI-PDHA/PEG-PDHA/PTX/siSna/siTwi

Method 2

Type: Physical formation
Source:
Starting materials
  1. lzws
Product

PEI-PDHA/PEG-PDHA/PTX/siSna/siTwi

Method 3

Type: Physical formation
Source:
Starting materials
  1. wBB5
Product

PEI-PDHA/PEG-PDHA/PTX/siSna/siTwi

Method 4

Type: Physical formation
Source:
Starting materials
  • polyethyleneimine-block-poly[(1,4-butanediol)-diacrylate-β-5-hydroxyamylamine]
  • polyethylene glycol-block-poly[(1,4-butanediol)-diacrylate-β-5-hydroxyamylamine]
  • Paclitaxel
  1. sJjdcbbuPyXekDGZZNOFJHHyoa
  2. J976
Product

PEI-PDHA/PEG-PDHA/PTX/siSna/siTwi

Method 5

Type: Physical formation
Source:
Starting materials
  1. oxCH
Product

PEI-PDHA/PEG-PDHA/PTX/siSna/siTwi

References

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