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sorafenib-loaded Alexa Fluor 488-labeled and DOTA-modified undecylenic acid-modified thermally hydrocarbonized porous silicon nanoparticles

Based on

1 Articles
2015 Most recent source

Composition

1

Alexa Fluor 488-labeled and DOTA-modified undecylenic acid-modified thermally hydrocarbonized porous silicon nanoparticles

UnTHCPSi-Alexa488-DBCO-DOTA NP
Type Nano Material
Formula
Role raw materials
2

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
Hsd:NMRI-Foxnl<sup>nu/nu</sup> mouse with prostate cancer PC3-MM2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. DIVF7CuitgIWEg9
Product

sorafenib-loaded Alexa Fluor 488-labeled and DOTA-modified undecylenic acid-modified thermally hydrocarbonized porous silicon nanoparticles

Size: not specified

Medium/Support: none

References

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