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vorinostat-loaded PLGA-lecithin-PEG core-shell NP

Based on

1 Articles
2015 Most recent source

Composition

1

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role core
2

N-Hydroxy-N`-phenyloctanediamide

suberanilohydroxamic acid vorinostat ZolinzaTM SAHA
Type Single Compound
Formula C14H20N2O3
Role loaded material
3

mixture of substance based on (1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-carboxy(polyethylene glycol)2000/1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-carboxy(polyethylene glycol)2000/soybean lecithin/soybean lecithin)

Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
colon cancer HCT116 cells

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Preparation

References

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