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iron oxide nanoparticle/doxorubicin-loaded chitosan-conjugated Pluronic F68-based multifunctional nano-carriers

Based on

1 Articles
2015 Most recent source

Composition

1

chitosan-conjugated Pluronic F68-based polymer

Type Complex Compound
Formula
Role core
2

iron oxide nanoparticle/doxorubicin complexes

IONP/DOX complexes
Type Nano Material
Formula
Role loaded material
3

N-hydroxysuccinimide ester modified Cy5.5

cyanine 5.5 N-hydroxysuccinimide ester cyanine5.5 N-hydroxysuccinimide ester hydroxysuccinimide ester of Cy5.5 Cy5.5 N-hydroxysuccinimide ester Cy5.5-N-hydroxysuccinimide ester cyanine 5.5 NHS ester Cyanine5.5 NHS ester Cy5.5 NHS ester Cy5.5-NHS ester Cy5.5-NHS-ester cyanine dye Cy5.5-NHS NHS-Cy5.5 Cy5.5
Type Single Compound
Formula C44H46N3O4Cl
Role layer
4

α-maleimide-ω-N-hydroxysuccinimide ester polyethylene glycol

NHS-PEG-MAL MAL-PEG-NHS
Type Polymer
Formula
Role layer
5

thiolated trastuzumab

thiolated herceptin
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
doxorubicin release dependent on media pH

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Applications

Area Application Nanomaterial Variant Source
diagnostics

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
MCF-7 cells

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Preparation

Method 1

Type: Physical formation
Source:
  1. XXlki67EzMw012U
Product

iron oxide nanoparticle/doxorubicin-loaded chitosan-conjugated Pluronic F68-based multifunctional nano-carriers

Hydrodynamic diameter: ~ 130 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. vmxDcFSrb
Product

iron oxide nanoparticle/doxorubicin-loaded chitosan-conjugated Pluronic F68-based multifunctional nano-carriers

Size: not specified

Medium/Support: none

References

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