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PEG-PAMAM-cis-aconityl-DOX conjugate

Based on

1 Articles
2014 Most recent source

Composition

1

PAMAM dendrimer G4

Type Polymer
Formula
Role core
2

cis-aconitic anhydride-functionalized doxorubicin

doxorubicin-cis-aconityl unit DOX-cis-aconityl unit CA-DOX
Type Single Compound
Formula -C33H33N2O15
Role layer
3

β-mercaptoethanol-quenched N-hydroxysulfosuccinimide-PEG-maleimide unit

β-mercaptoethanol-quenched NHS-PEG-MAL unit
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
glioma C6 cell spheroids

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
Product

PEG-PAMAM-cis-aconityl-DOX conjugate

Hydrodynamic diameter: 18.04 - 20.40 nm

Medium: DLS medium

Support: none

References

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