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β-lapachone diester encapsulated poly(ethylene glycol)-b-poly(D,L-lactic acid) micelles

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(ethylene glycol)-block-poly(D,L-lactic acid) block copolymer

PEG-b-PLA block copolymer
Type Polymer
Formula
Role carriers
2

β-lapachone dipentyl ester

β-lap diethyl ester
Type Single Compound
Formula C27H36O5
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release in presence of porcine liver esterase

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
A549 non-small cell lung cancer cells overexpressing quinone oxidoreductase 1 (NQO1)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-block-poly(D,L-lactic acid) block copolymer
  • β-lapachone dipentyl ester
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Product

β-lapachone diester encapsulated poly(ethylene glycol)-b-poly(D,L-lactic acid) micelles

References

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