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paclitaxel-loaded micellar solution of PEO113(-b-PLL43)-b-PCL71

Based on

1 Articles
2013 Most recent source

Composition

1

self-assembled micelles from ABC-type miktoarm star polypeptide hybrid copolymer consisting of poly(ethylene oxide), poly(L-lysine), and poly(ε-caprolactone) arms

self-assembled micelles from ABC-type miktoarm star polypeptide hybrid copolymers consisting of PEO(-b-PLL)-b-PCL micellar nanoparticles based on ABC-type miktoarm star polypeptide hybrid copolymer PEO(-b-PLL)-b-PCL PEO113(-b-PLL43)-b-PCL71 micelles in aqueous solution at pH 7.4 aqueous dispersion of PEO113(-b-PLL43)-b-PCL71 micelles PEO113(-b-PLL43)-b-PCL71 micellar nanoparticles PEO113(-b-PLL43)-b-PCL71 micelles PEO(-b-PLL)-b-PCL micelles
Type Nano Material
Formula
Role carriers
2

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source
paclitaxel release dependent on pH of phosphate-buffered saline

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
HeLa cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • polypeptide hybrid copolymer consisting of poly(ethylene oxide), poly(L-lysine), and poly(ε-caprolactone) arms
  • water
  • Paclitaxel
Product

paclitaxel-loaded micellar solution of PEO113(-b-PLL43)-b-PCL71

References

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