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polyvinylpyrrolidone/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Based on

3 Patents
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

megestrol acetate

Type Single Compound
Formula C24H32O4
Role core
2

polyvinylpyrrolidone

PVP
Type Polymer
Formula
Role layer
3

sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate

sodium 1,4-bis(2-ethylhexyl)sulfosuccinate sodium bis(2-ethylhexyl)-sulfosuccinate sodium bis(2-ethylhexyl)sulfosuccinate dioctyl sulfosuccinate sodium salt dioctyl sodium sulfosuccinate docusate sodium sodium docusate Docusate sodium Aerosol OT aerosol OT NaAOT DOSS AOT
Type Single Compound
Formula C20H37NaO7S
Role layer

Properties

General physical and chemical properties

Property Value Source
physical stability dependent on temperature

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
laser diffraction spectroscopy

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  • polyvinylpyrrolidone
  1. yFxjN4C0ImTz7BUmWP5
Product

polyvinylpyrrolidone/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  • polyvinylpyrrolidone
  1. h1nuyWvyzAVcqY22FPp
Product

polyvinylpyrrolidone/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  • polyvinylpyrrolidone
  1. 00eCCuRM17DYkzP6cxP
Product

polyvinylpyrrolidone/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

References

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