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HPMC/DOSS-coated megestrol nanoparticles dispersion

Based on

3 Patents
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

megestrol acetate

Type Single Compound
Formula C24H32O4
Role core
2

hydroxypropyl methylcellulose

HPMC
Type Biomolecule
Formula
Role layer
3

sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate

sodium 1,4-bis(2-ethylhexyl)sulfosuccinate sodium bis(2-ethylhexyl)-sulfosuccinate sodium bis(2-ethylhexyl)sulfosuccinate dioctyl sulfosuccinate sodium salt dioctyl sodium sulfosuccinate Docusate sodium docusate sodium sodium docusate Aerosol OT aerosol OT NaAOT DOSS AOT
Type Single Compound
Formula C20H37NaO7S
Role layer

Properties

General physical and chemical properties

Property Value Source
physical stability

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
laser diffraction spectroscopy

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Biological effects

Biological system Test details Source
fasted male human

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • hydroxypropyl methylcellulose
  • megestrol acetate
See all (4)
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  2. RUSxypmpy5Ry50AYNmyC53UdhR1
  3. bpe0oI
Product

HPMC/DOSS-coated megestrol nanoparticles dispersion

Method 2

Type: Physical formation
Source:
Starting materials
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • hydroxypropyl methylcellulose
  • megestrol acetate
See all (4)
  1. bmyMaoNOts4ALWcprC6
  2. iiX2c1vOTg4IqMnO7BpkS6Sd0h0
  3. aaMgLk
Product

HPMC/DOSS-coated megestrol nanoparticles dispersion

References

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