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poly(vinyl acetate-co-vinyl pyrrolidone)/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Based on

3 Patents
2015 Most recent source

Composition

1

megestrol acetate

Type Single Compound
Formula C24H32O4
Role core
2

poly(vinyl acetate-co-vinyl pyrrolidone)

Plasdone® S630
Type Polymer
Formula
Role layer
3

sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate

sodium 1,4-bis(2-ethylhexyl)sulfosuccinate sodium bis(2-ethylhexyl)-sulfosuccinate sodium bis(2-ethylhexyl)sulfosuccinate dioctyl sulfosuccinate sodium salt dioctyl sodium sulfosuccinate Docusate sodium docusate sodium sodium docusate Aerosol OT aerosol OT NaAOT DOSS AOT
Type Single Compound
Formula C20H37NaO7S
Role layer

Properties

General physical and chemical properties

Property Value Source
physical stability dependent on temperature

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
laser diffraction spectroscopy

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(vinyl acetate-co-vinyl pyrrolidone)
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  1. YFYsqSmKsVoDccDv2tS
Product

poly(vinyl acetate-co-vinyl pyrrolidone)/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(vinyl acetate-co-vinyl pyrrolidone)
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  1. GRCNwSyDmz5SXtTv2HC
Product

poly(vinyl acetate-co-vinyl pyrrolidone)/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(vinyl acetate-co-vinyl pyrrolidone)
  • sodium 1,4-bis(2-ethylhexoxy)-1,4-dioxobutane-2-sulfonate
  • megestrol acetate
  1. Eiy8LhKO6LjRFi6IpEh
Product

poly(vinyl acetate-co-vinyl pyrrolidone)/dioctyl sodium sulfosuccinate-coated megestrol acetate nanoparticles

References

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