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2`-O-methyl-modified TNF-α-specific siRNA-loaded chitosan/L-cysteine hydrochloride/sodium tripolyphosphate nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

chitosan/L-cysteine hydrochloride/sodium tripolyphosphate/2`-O-methyl-modified TNF-α-specific siRNA mixture

Type Complex Compound
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
scanning electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
Caco-2 cell line (human colon adenocarcinoma)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • chitosan
  1. Nvcsgmu3TTDj2AF0q44n4ahjyjicnYjJ92gcmNT4oIrKlI
  2. J1Mbuln
Product

2`-O-methyl-modified TNF-α-specific siRNA-loaded chitosan/L-cysteine hydrochloride/sodium tripolyphosphate nanoparticles

Size: 149 - 157 nm

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • chitosan
  1. KEfvPxyRX6ghkulfvZHOVmUlCYxniW9ASji7j4BsW6gZDu
  2. 59XgEeq
Product

2`-O-methyl-modified TNF-α-specific siRNA-loaded chitosan/L-cysteine hydrochloride/sodium tripolyphosphate nanoparticles

Size: 153 nm

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Product

2`-O-methyl-modified TNF-α-specific siRNA-loaded chitosan/L-cysteine hydrochloride/sodium tripolyphosphate nanoparticles

Size: not specified

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
Starting materials
  • chitosan
  1. dUqb0lG5mhLzZUIBFOtISNc0Z3DeOLpLOCpBQtYTkinaR2
  2. rA8g1LC
Product

2`-O-methyl-modified TNF-α-specific siRNA-loaded chitosan/L-cysteine hydrochloride/sodium tripolyphosphate nanoparticles

Size: 110 - 126 nm

Medium: phosphate buffer solution

Support: none

References

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