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doxorubicin-loaded 6-(2-nitroimidazole)hexylamine-carboxymethyl dextran nanoparticles

Based on

1 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

6-(2-nitroimidazole)hexylamine

Type Single Compound
Formula C9H16N4O2
Role core
2

carboxymethyl dextran

CM-Dex
Type Biomolecule
Formula
Role layer
3

doxorubicin hydrogen chloride

adriblastin hydrochloride doxorubicin hydrochloride adriamycin hydrochloride doxorubicin hydrochoride adriblastin HCl salt adriamycin HCl salt DOX hydrochloride DXR hydrochloride doxorubicin HCl DOX*HCl DOX-HCl DOX·HCl DXR HCl DXR*HCl Dox HCl Dox*HCl DOXS
Type Single Compound
Formula C27H29NO11*HCl
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on hypoxic conditions

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Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
athymic nude mouse bearing SCC7 tumor

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • doxorubicin hydrogen chloride
  1. jSO3Zt3tf6dMtxc4Jr4A7
  2. O7KgSvjISm17S
Product

doxorubicin-loaded 6-(2-nitroimidazole)hexylamine-carboxymethyl dextran nanoparticles

References

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