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camptothecin-loaded cationic chitosan-coated cationic poly-ε-caprolactone nanocapsules

Based on

1 Articles
2015 Most recent source

Composition

1

cationic chitosan-coated amphiphilic cyclodextrin nanocapsules

cationic CS-coated CD nanocapsules
Type Nano Material
Formula
Role carriers
2

(S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione

1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione (S)-(+)-camptothecin camptothecin CPT CMT CP
Type Single Compound
Formula C20H16N2O4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human adenocarcinoma Caco-2 cell line

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Preparation

Method 1

Type: Physical formation
Source:
  1. oKr
Product

camptothecin-loaded cationic chitosan-coated cationic poly-ε-caprolactone nanocapsules

Hydrodynamic diameter: 264.9 nm

Medium: simulated intestinal fluid

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  1. d5Zh3Jw
Product

camptothecin-loaded cationic chitosan-coated cationic poly-ε-caprolactone nanocapsules

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  1. DnY9HCQ
Product

camptothecin-loaded cationic chitosan-coated cationic poly-ε-caprolactone nanocapsules

Size: not specified

Medium/Support: none

Method 4

Type: Physical formation
Source:
  1. OkD
Product

camptothecin-loaded cationic chitosan-coated cationic poly-ε-caprolactone nanocapsules

Hydrodynamic diameter: 185.9 nm

Medium: simulated gastric fluid

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  1. g8T7yo2
Product

camptothecin-loaded cationic chitosan-coated cationic poly-ε-caprolactone nanocapsules

Hydrodynamic diameter: 192 - 216 nm

Medium: water

Support: none

References

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