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ovalbumin protein and Poly(I:C)-encapsulated poly(lactic-co-glycolic acid) nanoparticles modified with IgG2a antibody

Based on

1 Articles
2015 Most recent source

Composition

1

ovalbumin protein

OVA
Type Biomolecule
Formula
Role core
2

Poly(I:C) (TLR3L)

TLR3L ligand Poly(I:C)
Type Biomolecule
Formula
Role loaded material
3

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role layer
4

DSPE-PEG(2000) succinic acid

Type Polymer
Formula
Role loaded material
5

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

mPEG 2000 PE
Type Polymer
Formula
Role loaded material
6

mouse IgG2a

IgG2a
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
WT C57BL/6 mouse bone marrow dendritic cells (BMDC)

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • Poly(I:C) (TLR3L)
  • ovalbumin protein
  1. oyTcl7YRs65ix69m
  2. 4MzyJhGaD0N6X8HKEWsQhNKnN
  3. 7a1HwSWIFt04L7HPcXCj8Q4dzg
Product

ovalbumin protein and Poly(I:C)-encapsulated poly(lactic-co-glycolic acid) nanoparticles modified with IgG2a antibody

Diameter: 172.4 - 224.0 nm

Medium/Support: none

References

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