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ovalbumin protein, Poly(I:C) and Pam3CSK4-encapsulated poly(lactic-co-glycolic acid) nanoparticles modified with αCD40 antibody

Based on

1 Articles
2015 Most recent source

Composition

1

ovalbumin protein

OVA
Type Biomolecule
Formula
Role core
2

Pam3Csk4 (TLR2L)

TLR2L ligand Pam3CSK4
Type Biomolecule
Formula
Role loaded material
3

Poly(I:C) (TLR3L)

TLR3L ligand Poly(I:C)
Type Biomolecule
Formula
Role loaded material
4

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role layer
5

DSPE-PEG(2000) succinic acid

Type Polymer
Formula
Role loaded material
6

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt)

mPEG 2000 PE
Type Polymer
Formula
Role loaded material
7

murine agonistic αCD40 mAb

FGK45
Type Biomolecule
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
TC-1 tumor bearing mouse

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • Pam3Csk4 (TLR2L)
  • Poly(I:C) (TLR3L)
  • ovalbumin protein
  1. 6261fvOC6hnkohcw
  2. MoFWrJ4mOHBZX3wP7PG5zmzjA
  3. ffqcQ6cKULUj2qZFdPGG3kE3bk
Product

ovalbumin protein, Poly(I:C) and Pam3CSK4-encapsulated poly(lactic-co-glycolic acid) nanoparticles modified with αCD40 antibody

Diameter: 192.3 - 292.3 nm

Medium/Support: none

References

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