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irinotecan- and cisplatin-containing nanoparticles

Based on

1 Patents
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PLGA-mPEG5K

Type Polymer
Formula
Role raw materials
2

dual drug mixture

Type Complex Compound
Formula
Role loaded material

Properties

Applications

Characterization

Biological effects

Biological system Test details Source
human prostatic carcinoma PSMA-overexpressing LNCaP cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • PLA-succinic acid-conjugated irinotecan
  • PLA-succinic acid-conjugated cisplatin
  • PLGA-mPEG5K
  1. u3YNz7EHYHJ8Zgz4SUv9YjpXDcl
Product

irinotecan- and cisplatin-containing nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • PLA-succinic acid-conjugated irinotecan
  • PLA-succinic acid-conjugated cisplatin
  • PLGA-mPEG5K
  1. Almzvsy4tuRjt6U4OqvPWNBKeHH
Product

irinotecan- and cisplatin-containing nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • PLA-succinic acid-conjugated irinotecan
  • PLA-succinic acid-conjugated cisplatin
  • PLGA-mPEG5K
  1. iN9R7hsshheQ6wmlf7iKuFPChc3
Product

irinotecan- and cisplatin-containing nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • PLA-succinic acid-conjugated irinotecan
  • PLA-succinic acid-conjugated cisplatin
  • PLGA-mPEG5K
  1. Y2gnLRJdSPMzpr82kh1UIuEHenx
Product

irinotecan- and cisplatin-containing nanoparticles

Method 5

Type: Physical formation
Source:
Starting materials
  • PLA-succinic acid-conjugated irinotecan
  • PLA-succinic acid-conjugated cisplatin
  • PLGA-mPEG5K
  1. JTlOcLBVTuumcDehstWPPpeqSOP
Product

irinotecan- and cisplatin-containing nanoparticles

References

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