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F2 methotrexate-loaded PEGylated DPPC/cholesterol liposomes

Based on

1 Articles
2012 Most recent source

Composition

1

phosphate-buffered saline

PBS
Type Complex Compound
Formula
Role core
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material
3

1,2-dipalmitoyl-sn-glycero-phosphatidylcholine

dipalmitoyl phosphatidylcholine dipalmitoylphosphatidylcholine DPPC
Type Single Compound
Formula C40H80NO8P
Role layer
4

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- [methoxy(polyethylene glycol)-2000]

DSPE-MPEG 2000
Type Polymer
Formula
Role layer
5

cholesterol

Type Single Compound
Formula C27H46O
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • cholesterol
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N- [methoxy(polyethylene glycol)-2000]
  1. PUsfzttDJ0ZYQ0pgn2WMMiWoL62SCKSmm0mFud0LAQHwdSRfXah
Product

F2 methotrexate-loaded PEGylated DPPC/cholesterol liposomes

Size: ~ 210 nm

Medium: phosphate-buffered saline

Support: none

References

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