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doxorubicin-loaded prostate cancer-binding peptide-conjugated cholesterol-modified glycol chitosan micelles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

prostate-specific membrane antigen-targeted glycol chitosan micelles

prostate cancer-binding peptides-modified polymeric micelles PCP-conjugated cholesterol-modified glycol chitosan micelles PSMA-targeted glycol chitosan micelles PCP-conjugated CHGC micelles PCP-modified nanoparticles PCP-conjugated micelles PCP-modified micelles PCP-CHGC micelles
Type Nano Material
Formula
Role raw materials
2

adriblastin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
cumulative drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
transmission electron microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
male BALB/c nude mouse bearing LNCaP cancer xenograft

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Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • doxorubicin hydrogen chloride
  1. 1AmG2j2Mlj5ak
  2. A7UvX33Sv5
Product

doxorubicin-loaded prostate cancer-binding peptide-conjugated cholesterol-modified glycol chitosan micelles

Diameter: ~ 240 nm

Hydrodynamic diameter: 248 - 338 nm

Medium/Support: none

References

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