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PTX-loaded nanosized lipid carriers

Based on

1 Articles
2015 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

1-stearoyl-rac-glycerol

glycerin monostearate glycerol monostearate glyceryl monostearate glycerol-3 stearate monostearin GMS MS
Type Single Compound
Formula C21H42O4
Role core
2

lipid material

Type Complex Compound
Formula
Role layer
3

Paclitaxel

Plaxicel Abraxane Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug entrapment efficiency

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • 1-stearoyl-rac-glycerol
  • Paclitaxel
  1. oZgzO8J
  2. rrOGsVr
Product

PTX-loaded nanosized lipid carriers

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • 1-stearoyl-rac-glycerol
  • Paclitaxel
  1. T9sBuN3
  2. EF3g41O
Product

PTX-loaded nanosized lipid carriers

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • 1-stearoyl-rac-glycerol
  • Paclitaxel
  1. iM4kG1d
  2. ZxIXh6t
Product

PTX-loaded nanosized lipid carriers

Hydrodynamic diameter: 508.3 - 554.5 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • 1-stearoyl-rac-glycerol
  • Paclitaxel
  1. xd6h0d4
  2. QY2LJWy
Product

PTX-loaded nanosized lipid carriers

Hydrodynamic diameter: 523.4 - 600.0 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • oleic acid
  • 1-stearoyl-rac-glycerol
  • Paclitaxel
  1. XnmB2Tf
  2. 6OVvI9O
Product

PTX-loaded nanosized lipid carriers

Size: not specified

Medium: phosphate buffer solution

Support: none

References

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