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docetaxel-loaded poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles

Based on

1 Articles
2013 Most recent source

Composition

1

PLA-TPGS nanoparticles

Type Nano Material
Formula
Role carriers
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source

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Applications

Area Application Source

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Characterization

Method Source

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Biological effects

Biological system Test details Source

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  1. kHn
  2. VEG8f
  3. BjMnUU58nY
Product

docetaxel-loaded poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate
  1. UZh
  2. JnkCT
  3. M6npK1TLw4DuXCBoFzSB
Product

docetaxel-loaded poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate
  1. OQR
  2. JsPa9
  3. C274BS5R6Dn
  4. IN7azFV67ITLDE
Product

docetaxel-loaded poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles

Method 4

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate
  1. hUL
  2. hdiWy
  3. V4v9uSbRLG
Product

docetaxel-loaded poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles

Method 5

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate
  1. vYT
  2. GHkRp
  3. eocSXfmPzvr
  4. mmp92Ms1CSxfx3
Product

docetaxel-loaded poly(lactide)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles

References

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