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fluconazole-loaded Poloxamer 188/N-(carbonyl-methoxypolyethyleneglycol 2000)-1,2 sn-glycero-3-phosphoethanolamine nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

fluconazole

Type Single Compound
Formula C13H12F2N6O
Role core
2

Poloxamer 188

P188
Type Polymer
Formula
Role layer
3

N-(carbonyl-methoxypolyethyleneglycol 2000)-1,2 sn-glycero-3-phosphoethanolamine

mPEG2000-DSPE
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
HBMEC human brain microvascular endothelial cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • N-(carbonyl-methoxypolyethyleneglycol 2000)-1,2 sn-glycero-3-phosphoethanolamine
  • aqueous solution
  • Poloxamer 188
See all (4)
Product

fluconazole-loaded Poloxamer 188/N-(carbonyl-methoxypolyethyleneglycol 2000)-1,2 sn-glycero-3-phosphoethanolamine nanoparticles

Size: 894 nm

Medium: aqueous solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • N-(carbonyl-methoxypolyethyleneglycol 2000)-1,2 sn-glycero-3-phosphoethanolamine
  • Poloxamer 188
  1. 4GROzwNs2Rvs073cBKCe8q
Product

fluconazole-loaded Poloxamer 188/N-(carbonyl-methoxypolyethyleneglycol 2000)-1,2 sn-glycero-3-phosphoethanolamine nanoparticles

Size: 1143 nm

Medium: HEPES buffer

Support: none

References

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