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celastrol-loaded poly(ethylene glycol)-block-poly(ε-caprolactone) micelles

Based on

1 Articles
2012 Most recent source

Composition

1

3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleano-1(10),3,5,7-tetraen-29-oic acid

tripterine celastrol tripterin
Type Single Compound
Formula C29H38O4
Role core
2

poly(ethylene glycol)-block-poly(ε-caprolactone) copolymer

PEG-b-PCL
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human umbilical vein endothelial cells (HUVEC)

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-block-poly(ε-caprolactone) copolymer
  • 3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleano-1(10),3,5,7-tetraen-29-oic acid
  1. 7n7R3sfTvwzpmLTQhAPuqR
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  3. JDIlXi2u4E
Product

celastrol-loaded poly(ethylene glycol)-block-poly(ε-caprolactone) micelles

Diameter: ~ 48 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

celastrol-loaded poly(ethylene glycol)-block-poly(ε-caprolactone) micelles

Hydrodynamic diameter: ~ 40 - 70 nm

Medium: DLS medium

Support: none

References

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