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doxorubicin hydrochloride-loaded PLGA:PEG triblock copolymer-coated Fe3O4 nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

iron(II,III) oxide

magnetite
Type Single Compound
Formula Fe3O4
Role core
2

poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid)

PLGA-PEG triblock copolymer
Type Polymer
Formula
Role layer
3

doxorubicin hydrogen chloride

adriblastin hydrochloride doxorubicin hydrochloride adriamycin hydrochloride doxorubicin hydrochoride adriblastin HCl salt adriamycin HCl salt DOX hydrochloride DXR hydrochloride doxorubicin HCl DOX*HCl DOX-HCl DOX·HCl DXR HCl DXR*HCl Dox HCl Dox*HCl DOXS
Type Single Compound
Formula C27H29NO11*HCl
Role loaded material

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
drug delivery

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Characterization

Biological effects

Biological system Test details Source
lung cancer A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid)
  • Fe3O4 nanoparticles
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  2. 2tQA0YyDuYxjlik5qOEZ6m7fNaj9Cn9nN
  3. ON2CdvfqQx
Product

doxorubicin hydrochloride-loaded PLGA:PEG triblock copolymer-coated Fe3O4 nanoparticles

Method 2

Type: Physical formation
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid)
  • Fe3O4 nanoparticles
  1. JDAvn6KODEpQ4y9SliTGBY
  2. vTbseHhwoeJVJFjL9we5ClLTBJsN4Nujk
  3. xYbJcG5tx2
Product

doxorubicin hydrochloride-loaded PLGA:PEG triblock copolymer-coated Fe3O4 nanoparticles

Method 3

Type: Physical formation
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid)
  • Fe3O4 nanoparticles
  1. JeKOBwzjPOSwkK7A3a0FUQ
  2. os1KmITiKJ5tzhqx342J8HBtLEARiqcEN
  3. w8zKZiPWpf
Product

doxorubicin hydrochloride-loaded PLGA:PEG triblock copolymer-coated Fe3O4 nanoparticles

References

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