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doxorubicin hydrochloride-loaded PLGA:PEG triblock copolymer-coated Fe3O4 nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

iron(II,III) oxide

magnetite
Type Single Compound
Formula Fe3O4
Role core
2

poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid)

PLGA-PEG triblock copolymer
Type Polymer
Formula
Role layer
3

doxorubicin hydrogen chloride

doxorubicin hydrochloride adriblastin hydrochloride adriamycin hydrochloride doxorubicin hydrochoride adriblastin HCl salt adriamycin HCl salt DOX hydrochloride DXR hydrochloride doxorubicin HCl Dox HCl Dox*HCl DOX*HCl DOX-HCl DOX·HCl DXR HCl DXR*HCl DOXS
Type Single Compound
Formula C27H30ClNO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
lung cancer A549 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid)
  • Fe3O4 nanoparticles
  1. ymthmNAoLV9DAH3cX2TXCP
  2. rfW2su1jg5sbecxyFMOfePvVzcUVvzjD5
  3. JGpGzY8cVX
Product

doxorubicin hydrochloride-loaded PLGA:PEG triblock copolymer-coated Fe3O4 nanoparticles

Size: 35 - 65 nm

Size: ~ 20 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid)
  • Fe3O4 nanoparticles
  1. aFYEy8BCKIW4Eyouj7mNvn
  2. kCHkYtPTbabdP1PD32AFWtO7IaFCMOg2Z
  3. oU64eZ5iME
Product

doxorubicin hydrochloride-loaded PLGA:PEG triblock copolymer-coated Fe3O4 nanoparticles

Size: 22 - 48 nm

Size: ~ 20 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • doxorubicin hydrogen chloride
  • poly(lactic acid-co-glycolic acid)-block-poly(ethylene glycol)-block-poly(lactic acid-co-glycolic acid)
  • Fe3O4 nanoparticles
  1. CBSa0ORbl7ZpSPCMSLjpYs
  2. uVUZ2H4QWbMNIlnLwQjNCsqcxnWyEJTu9
  3. 2bLf3OA9Wm
Product

doxorubicin hydrochloride-loaded PLGA:PEG triblock copolymer-coated Fe3O4 nanoparticles

Size: 18 - 40 nm

Size: ~ 20 nm

Medium: water

Support: none

References

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