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doxorubicin-loaded O-maleyl chondroitin sulfate functionalized mesoporous silica nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

mesoporous silica nanoparticles

MSN
Type Nano Material
Formula
Role core
2

(3-aminopropyl)-triethoxysilane moiety

(3-aminopropyl)trimethoxysilane moiety (3-aminopropyl)triethoxysilane moiety γ-aminopropyltriethoxy silane moiety 3-aminopropyltrimethoxysilane moiety 3-aminopropyltriethoxysilane moiety γ-aminopropyltriethoxysilane moiety (3-aminopropyl)trioxysilane moiety (3-aminopropyl)silanetrioxy group 3-aminopropylsilanetrioxy group 3-aminopropylsiloxy fragment 3-aminopropyl silane moiety 3-aminopropylsilane moiety γ-APTES moiety 3-APTS moiety APTES moiety APTMS moiety AMPS moiety APTS moiety APS moiety
Type Single Compound
Formula -C3H8NO3Si-
Role layer
3

O-maleyl chondroitin sulfate, polymerized

cross-linked NMChS
Type Biomolecule
Formula
Role layer
4

doxorubicin

adriblastin adriamycin DOX DXR
Type Single Compound
Formula C27H29NO11
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on pH

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Nanomaterial Variant Source
HeLa cells

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Preparation

Method 1

Type: Chemical synthesis
Source:
  1. 3TVy7veCGOAA7RYkC2xaOhio4JmUDy9yeucTxzJBNmJQzN
Product

doxorubicin-loaded O-maleyl chondroitin sulfate functionalized mesoporous silica nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 2

Type: Chemical synthesis
Source:
  1. euGHg29ILLTFINVZSZMorRFWvkIiSFIX0UEVLNMlyLQWdi
Product

doxorubicin-loaded O-maleyl chondroitin sulfate functionalized mesoporous silica nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

Method 3

Type: Chemical synthesis
Source:
  1. HfuclEB8YPzFhHhbLmdNguRNEJ8R9AajJTEcjcyI8YEbhd
Product

doxorubicin-loaded O-maleyl chondroitin sulfate functionalized mesoporous silica nanoparticles

Size: not specified

Medium: phosphate buffer solution

Support: none

References

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