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PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Based on

22 Articles
1 Patents
2017 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

mesoporous silica coated upconversion nanoparticles

mesoporous silica coated UCNP silica coated UCN
Type Nano Material
Formula
Role carriers
2

Paclitaxel

Abraxane Plaxicel Paxene Taxol PAC PCL PTX PX
Type Single Compound
Formula C47H51NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Zeta potential

Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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transmission electron microscopy

Biological effects

Biological system Test details Nanomaterial Variant Source
4T1 tumor-bearing BALB/c mouse

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(D,L lactide-co-glycolide)
  • Paclitaxel
  1. kgyneK9tH4yVmBFWXbFU7
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(ethylene glycol)-block-poly(D,L-lactic acid)
  • Paclitaxel
  1. DYf6XWlTf6Myj00Pcy5OlmdphDO
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Hydrodynamic diameter: 25.6 - 48.4 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • methoxy-poly(ethylene glycol)-co-poly(trimethylene carbonate)
  • Paclitaxel
  1. 1MFbH7wrC06ss3oSp1OdCje4
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Size: not specified

Medium/Support: none

Method 4

Type: Chemical synthesis
Source:
  1. IlkO9d13raX7OBtXobsn6jifs
  2. HgSLZuO8
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Pore size: 3.4 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(caprolactone)-grafted dextran
  • Paclitaxel
  1. iBXtCg9kQAu7x3jrpMg2xOgrQT
Product

PTX-loaded chitosan/vitamin E succinate copolymer nanomicelles

Diameter: 210 - 240 nm

Medium/Support: none

References

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