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poly(L-γ-glutamyl-glutamine)-docetaxel conjugate nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

poly(L-γ-glutamyl-glutamine)-docetaxel conjugate

PGG-docetaxel conjugate PGG-DTX conjugate PGG-DTX
Type Biomolecule
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
H460 carcinoma-bearing female BALB/c nude mouse, 6-8 weeks of age

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Preparation

Method 1

Type: Chemical synthesis
Source:
Product

poly(L-γ-glutamyl-glutamine)-docetaxel conjugate nanoparticles

Diameter: 20 - 30 nm

Medium/Support: none

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • poly(L-γ-glutamylglutamine)
  1. Xj7XEoHh2OVpPpv2kXRg9Eve3msn1Rcu5di6Ioyd8P92TuNDTBjLgKmY06S1ScheW0rCVKyV6OLTqyo
  2. RzcvxLNngar32ZfGr6MA3bPGYoz8P5TrT8t23x
  3. JGUQIfx3h8XJ8NAF5hlLfCbsj5WTBxPDxQA9
Product

poly(L-γ-glutamyl-glutamine)-docetaxel conjugate nanoparticles

Size: 23.3 - 33.3 nm

Medium: water

Support: none

References

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