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camptothecin nanoparticles surface-coated with PEG-2000

Based on

1 Articles
2012 Most recent source

Composition

1

palmityl alcohol

hexadecan-1-ol 1-hexadecanol cetyl alcohol hexadecanol Sipol C16 CA
Type Single Compound
Formula C16H34O
Role core
2

Brij 78

Type Polymer
Formula
Role layer
3

methoxypoly(ethylene glycol)

mPEG
Type Polymer
Formula
Role layer
4

(S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione

1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione (S)-(+)-camptothecin camptothecin CPT CMT CP
Type Single Compound
Formula C20H16N2O4
Role loaded material

Properties

Applications

Area Application Source
medicine/veterinary

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Characterization

Biological effects

Biological system Test details Source
aggressive murine glioblastoma D54 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • palmityl alcohol
  1. EllZZyU
Product

camptothecin nanoparticles surface-coated with PEG-2000

Method 2

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • palmityl alcohol
  1. A7imb8D
Product

camptothecin nanoparticles surface-coated with PEG-2000

Method 3

Type: Physical formation
Source:
Starting materials
  • (S)-(+)-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-(4H,12H)-dione
  • palmityl alcohol
  1. vOH2dyV
Product

camptothecin nanoparticles surface-coated with PEG-2000

References

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