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cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

plasmid DNA/protamine/plasmid DNA nanoparticles

DNA/Pro/DNA nanoparticles DPD nanoparticles DPD
Type Nano Material
Formula
Role core
2

1,2-dioleoyl-sn-glycero-3-phosphoethanolamine/6-lauroxyhexyl lysinate mixture

DOPE/LHLN mixture
Type Complex Compound
Formula
Role layer

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human liver carcinoma HepG2 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • (9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 6-lauroxyhexyl lysinate
  1. b8mWAOoBSuYBvUwqa3o
  2. SAOfMiimKIHV7y4EVDd
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Hydrodynamic diameter: 155.1 - 161.9 nm

Medium: aqueous solution

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • (9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 6-lauroxyhexyl lysinate
  1. s0wvNa5zZHT3gMG9szb
  2. W6W17Lm0MEXI9IkzKaU
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Hydrodynamic diameter: 463.0 - 475.6 nm

Medium: aqueous solution

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • (9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 6-lauroxyhexyl lysinate
  1. cPco9eWQI6jVgJysCPc
  2. hYb1DrrfyaDoTmrlro6
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Hydrodynamic diameter: 131.7 - 137.5 nm

Medium: aqueous solution

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • (9Z)-9-octadecenoic acid (1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
  • 6-lauroxyhexyl lysinate
  1. aQU3Hfpt7Y6oHNuMLN8
  2. UPL8NdvqN2HgOTM9wKr
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Hydrodynamic diameter: 175.9 - 185.3 nm

Medium: aqueous solution

Support: none

Method 5

Type: Physical formation
Source:
Product

cationic liposome-coated plasmid DNA/protamine/plasmid DNA nanoparticles

Diameter: ~ 150 - 200 nm

Medium/Support: none

References

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