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ritonavir-loaded folate-Poloxamer 407/Poloxamer 407 nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

(5S,8S,10S,11S)-10-hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic acid 5-thiazolyl-methyl ester

ritonavir RTV
Type Single Compound
Formula C37H48N6O5S2
Role core
2

folate Poloxamer 407

folate-P407
Type Polymer
Formula
Role layer
3

Poloxamer 407

P407
Type Polymer
Formula
Role layer

Properties

General physical and chemical properties

Property Value Source
Zeta potential

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
HIV-1<sub>ADA</sub>-infected male NOD/scid-γ<sub>c</sub><sup>null</sup> mouse reconstituted with human peripheral blood lymphocytes

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • folate Poloxamer 407
  • Poloxamer 407
  1. K2whLpD0FuB7gnfAc5qSGI
Product

ritonavir-loaded folate-Poloxamer 407/Poloxamer 407 nanoparticles

References

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