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sorafenib-loaded solid lipid nanoparticles

Based on

1 Articles
2012 Most recent source

Composition

1

lipid mixture

Type Complex Compound
Formula
Role core
2

Poloxamer 188

Type Polymer
Formula
Role layer
3

4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide

sorafenib SFN SOR SF
Type Single Compound
Formula C21H16ClF3N4O3
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
rabbit

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
  • egg-phosphatidylcholine
  • glyceryl behenate
  1. ubiinec
  2. MEpEX8be
Product

sorafenib-loaded solid lipid nanoparticles

Hydrodynamic diameter: 101.22 - 115.24 nm

Medium: water

Support: none

References

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