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cell-penetrating peptide-coated tripterin-loaded nanostructured lipid carriers

Based on

1 Articles
2012 Most recent source

Composition

1

Precirol ATO-5/Labrafil M 1944CS mixture

Type Complex Compound
Formula
Role core
2

soybean lecithin

SLT
Type Complex Compound
Formula
Role layer
3

poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)

Poloxamer 188 Pluronic F68 F68
Type Polymer
Formula
Role layer
4

D-α-tocopheryl polyethylene glycol succinate 1000

TPGS
Type Polymer
Formula
Role layer
5

Ste-R6L2 cell-penetrating peptide

Ste-R6L2 CPP
Type Biomolecule
Formula
Role layer
6

3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleano-1(10),3,5,7-tetraen-29-oic acid

tripterine celastrol tripterin
Type Single Compound
Formula C29H38O4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

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Biological effects

Biological system Test details Nanomaterial Variant Source
beagle dog

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol succinate 1000
  • 3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleano-1(10),3,5,7-tetraen-29-oic acid
  • Labrafil M 1944CS
See all (5)
  1. IyLQYtIoLBfiPvwJ7WDacJRZ
Product

cell-penetrating peptide-coated tripterin-loaded nanostructured lipid carriers

Size: 95.1 - 136.7 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Product

cell-penetrating peptide-coated tripterin-loaded nanostructured lipid carriers

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol succinate 1000
  • 3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleano-1(10),3,5,7-tetraen-29-oic acid
  • Labrafil M 1944CS
See all (5)
  1. wXUW3S7DGSPkCqMGb0wSEUfV
Product

cell-penetrating peptide-coated tripterin-loaded nanostructured lipid carriers

Size: 154.6 - 223.0 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • D-α-tocopheryl polyethylene glycol succinate 1000
  • 3-hydroxy-9β,13α-dimethyl-2-oxo-24,25,26-trinoroleano-1(10),3,5,7-tetraen-29-oic acid
  • Labrafil M 1944CS
See all (5)
  1. VVUkFayFOrhcNdBQbvtaFCVy
Product

cell-penetrating peptide-coated tripterin-loaded nanostructured lipid carriers

Size: 108.3 - 145.1 nm

Medium: water

Support: none

References

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