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5-fluorouracil-loaded magnetic nanoaggregates

Based on

7 Articles
2016 Most recent source

Composition

1

glyceryl monostearate solid lipid nanoparticles

GMS SLN
Type Nano Material
Formula
Role carriers
2

5-fluoro-2,4(1H,3H)pyrimidinedione

5-Fluorouracil 5-fluorouracil fluorouracil Adrucil® Efudex® adrucil efudex 5-FU 5-Fu 5FU
Type Single Compound
Formula C4H3FN2O2
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
accumulated drug release

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Applications

Area Application Nanomaterial Variant Source
drug delivery

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
C57/BL6 murine metastatic melanoma B16F10 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. E5Cwlq3SjN8CQW5HOhP
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: not specified

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • n-hexadecyl palmitate
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. DX0fAV9WSZaBP8uG
  2. 4e6sojM8ANbkSYqp5jPxCTd
  3. SjcwvGi7t0z0Xl18iVIupQIFA43aOuib
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: 171 - 193 nm

Medium/Support: none

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • iron(II) sulphate heptahydrate
  • β-cyclodextrin
See all (5)
  1. QG5eO
  2. Uvmloe5z95B9hLqs
  3. HmVIB2Ao
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: ~ 82 nm

Medium/Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • 5-fluoro-2,4(1H,3H)pyrimidinedione
  • 1-stearoyl-rac-glycerol
  • poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol)
  1. g2LBuEaWDtb6Rijd
  2. klYqClBJSV9EyYNJqkJHht6
  3. 71AV98ba62WqUvGpbJoHmf0RKCCyjCyz
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: 144 - 186 nm

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  1. OhHVb
  2. Kz2fN9Zk5U5q1y4f
  3. pkDs3U22
Product

5-fluorouracil-loaded magnetic nanoaggregates

Size: ~ 82 nm

Medium/Support: none

References

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