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N-(2-aminoethyl)iminobis[N-(2-(oleoyl-cysteinyl-histidinyl-amino)ethyl)propionamide]/c(RGDfK)-polyethylene glycol-maleimide/anti-MIF short-interfering RNA nanoparticles in DPBS

Based on

1 Articles
2012 Most recent source

Composition

1

N-(2-aminoethyl)iminobis[N-(2-(oleoyl-cysteinyl-histidinyl-amino)ethyl)propionamide]

N-(1-aminoethyl)iminobis[N-(oleoylcysteinylhistinyl-1-aminoethyl)propionamide] EHCO
Type Single Compound
Formula C66H116N14O8S2
Role core
2

cyclic c(RGDfK)-PEG conjugate with maleimido end group

c(RGDfK)-polyethylene glycol-maleimide RGD-PEG-Mal
Type Polymer
Formula
Role layer
3

anti-MIF short-interfering RNA

anti-MIF siRNA siMIF
Type Biomolecule
Formula
Role loaded material

Properties

Applications

Area Application Source

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Characterization

Method Source

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Biological effects

Preparation

Method 1

Type: Chemical synthesis
Source:
Starting materials
  • Dulbecco's phosphate-buffered saline
  • N-(2-aminoethyl)iminobis[N-(2-(oleoyl-cysteinyl-histidinyl-amino)ethyl)propionamide]
  • cyclic c(RGDfK)-PEG conjugate with maleimido end group
  1. A4uh86nFiKh2zvRy
  2. JaDlRSF
Product

N-(2-aminoethyl)iminobis[N-(2-(oleoyl-cysteinyl-histidinyl-amino)ethyl)propionamide]/c(RGDfK)-polyethylene glycol-maleimide/anti-MIF short-interfering RNA nanoparticles in DPBS

Method 2

Type: Chemical synthesis
Source:
Starting materials
  • water
  • N-(2-aminoethyl)iminobis[N-(2-(oleoyl-cysteinyl-histidinyl-amino)ethyl)propionamide]
  • cyclic c(RGDfK)-PEG conjugate with maleimido end group
  1. 5ehvoXqVq3zlIfq6
  2. 2luTkBN
Product

N-(2-aminoethyl)iminobis[N-(2-(oleoyl-cysteinyl-histidinyl-amino)ethyl)propionamide]/c(RGDfK)-polyethylene glycol-maleimide/anti-MIF short-interfering RNA nanoparticles in DPBS

Method 3

Type: Chemical synthesis
Source:
Starting materials
  • Dulbecco's phosphate-buffered saline
  • N-(2-aminoethyl)iminobis[N-(2-(oleoyl-cysteinyl-histidinyl-amino)ethyl)propionamide]
  • cyclic c(RGDfK)-PEG conjugate with maleimido end group
  1. A1OjDz2bPXcM0pd1
  2. 8Ci2WVB
Product

N-(2-aminoethyl)iminobis[N-(2-(oleoyl-cysteinyl-histidinyl-amino)ethyl)propionamide]/c(RGDfK)-polyethylene glycol-maleimide/anti-MIF short-interfering RNA nanoparticles in DPBS

References

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