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polyethylenimine/antisense oligonucleotide nanosized complex

Based on

1 Articles
2011 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

PEI/ASON complex

Type Complex Compound
Formula
Role raw materials

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
colloidal stability in RPMI-1640 culture medium

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
atomic force microscopy

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/C nude mouse bearing human esophageal cancer EC9706 xenograft

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(iminoethylene)
  • β-D(+)-glucose
  • water
See all (5)
Product

polyethylenimine/antisense oligonucleotide nanosized complex

Hydrodynamic size: ~ 100 nm

Medium: mixture of substance based on (β-D(+)-glucose/β-D(+)-glucose/dextran 70/dextran 70/water/water)

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(iminoethylene)
  • β-D(+)-glucose
  • water
See all (5)
Product

polyethylenimine/antisense oligonucleotide nanosized complex

Hydrodynamic size: ~ 120 nm

Medium: mixture of substance based on (β-D(+)-glucose/β-D(+)-glucose/dextran 70/dextran 70/water/water)

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(iminoethylene)
  • β-D(+)-glucose
  • water
See all (5)
Product

polyethylenimine/antisense oligonucleotide nanosized complex

Hydrodynamic size: ~ 100 nm

Medium: mixture of substance based on (β-D(+)-glucose/dextran 70/water)

Support: none

Method 4

Type: Physical formation
Source:
Product

polyethylenimine/antisense oligonucleotide nanosized complex

Size: not specified

Medium/Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(iminoethylene)
  • β-D(+)-glucose
  • water
See all (5)
Product

polyethylenimine/antisense oligonucleotide nanosized complex

Hydrodynamic size: ~ 100 nm

Medium: mixture of substance based on (β-D(+)-glucose/β-D(+)-glucose/dextran 70/dextran 70/water/water)

Support: none

References

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