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dimethyldidodecylammonium bromide-modified doxorubicin-loaded poly(lactic-co-glycolic acid)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine core/shell particles

Based on

1 Articles
2012 Most recent source

Composition

1

doxorubicin-poly(lactic-co-glycolic acid) conjugate

DOX-PLGA conjugate
Type Polymer
Formula
Role core
2

N-dodecyl-N,N-dimethyldodecan-1-aminium bromide

dodecyl-N,N-dimethyl-1-dodecanaminium bromide didodecyl dimethylammonium bromide didodecyldimethylammonium bromide dimethyldidodecylammonium bromide dilauryldimethylammonium bromide dDDdMABr DDAB DMAB
Type Single Compound
Formula C26H56BrN
Role layer
3

1,2-dipalmitoyl-sn-glycero-phosphatidylcholine

dipalmitoyl phosphatidylcholine dipalmitoylphosphatidylcholine DPPC
Type Single Compound
Formula C40H80NO8P
Role layer

Properties

General physical and chemical properties

Property Value Source
drug release dependent on media pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
scanning electron microscopy

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Biological effects

Biological system Test details Source
Michigan Cancer Foundation-7 (MCF-7) cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  1. 6jqub5t8n2h2arffXF6Wk
  2. IyWvI
Product

dimethyldidodecylammonium bromide-modified doxorubicin-loaded poly(lactic-co-glycolic acid)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine core/shell particles

Method 2

Type: Physical formation
Source:
Starting materials
  • 1,2-dipalmitoyl-sn-glycero-phosphatidylcholine
  1. UAhRQEVEn856LQz54fEDm
  2. L6Bow
Product

dimethyldidodecylammonium bromide-modified doxorubicin-loaded poly(lactic-co-glycolic acid)/1,2-dipalmitoyl-sn-glycero-3-phosphocholine core/shell particles

References

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