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docetaxel-loaded lipid-based nanomicelles

Based on

1 Articles
2012 Most recent source

Composition

1

lipid-based nanomicelles

Type Nano Material
Formula
Role carriers
2

1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}

docetaxel Taxotere Dtxl Doc Dtx
Type Single Compound
Formula C43H53NO14
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug encapsulation efficiency

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Applications

Area Application Source
diagnostics

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Characterization

Method Source
transmission electron microscopy

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Biological effects

Biological system Test details Source
BALB/c nude mouse bearing luciferase-expressing human breast tumor MDA-MB-231 cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • 1,7β,10β-trihydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4,13α-triyl 4-acetate 2-benzoate 13-{(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoate}
  • Lipoid S100
  • Solutol HS15
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Product

docetaxel-loaded lipid-based nanomicelles

References

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