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vesicle-based polyplex

Based on

1 Articles
2012 Most recent source

Composition

1

Vacuous

Type
Formula
Role core
2

poly(n-butyl methacrylate)x-b-poly(N-acryloylmorpholine)y

PBMA-b-PNAM diblock copolymer PBMAx-b-PNAMy
Type Polymer
Formula
Role layer
3

plasmid DNA

pEGFP-N1 pDNA
Type Biomolecule
Formula
Role loaded material
4

N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium

(N-[1-(2, 3-dioleoyloxy)propyl]-N,N,N-trimethylammoniumsalt) 1,2-di(9Z-octadecenoyloxy)-3-trimethylammonium-propane N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium 1,2-di-(9Z-octadecenoyl)-3-trimethylammonium-propane 1,2-dioleoyloxy-3-trimethylammonium-propane 1,2-dioleoyl-3-(trimethylammonium)propane 1,2-dioleoyl-3-trimethyl-ammonium-propane 1,2-dioleoyl-3-trimethylammonium propane 1,2-dioleoyl-3-trimethylammonium-propane 1,2-dioleoyl-3-trimethylammonium-propan 1,2-dioleoyl-3-trimethylammoniumpropane DOTAP
Type Single Compound
Formula C42H80NO4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
Zeta potential

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Applications

Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
BALB/c nude mouse bearing human breast adenocarcinoma (MDA-MB-231) cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  1. CJpxLje3vSU
Product

vesicle-based polyplex

Size: not specified

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • N,N,N-trimethyl-2,3-bis[(9Z)-9-octadecenoyloxy]-1-propanaminium
  • poly(n-butyl methacrylate)x-b-poly(N-acryloylmorpholine)y
  • plasmid DNA
  1. G87oRQZ
Product

vesicle-based polyplex

Size: ~ 150 nm

Medium: water

Support: none

References

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