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emtansine-loaded star-shaped folate-core polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate copolymer nanoparticles

Based on

1 Articles
2014 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

star-shaped folate-core polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate copolymer

star-shaped FA-PLA-TPGS copolymer
Type Polymer
Formula
Role carriers
2

mertansine

emtansine DM1
Type Single Compound
Formula C35H48ClN3O10S
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
MCF-7/HER2(ER<sup>+</sup>, HER2-HIGH) human breast adenocarcinoma cell

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • star-shaped folate-core polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate copolymer
  • mertansine
  1. 7aSlMFWuulBSb3Y0H
  2. 2uX4e4ogSCruJBzMG5Q70KYSbEm0K
Product

emtansine-loaded star-shaped folate-core polylactide-D-α-tocopheryl polyethylene glycol 1000 succinate copolymer nanoparticles

References

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