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miR-150-loaded poly (D,L-lactide-co-glycolide)/polyethylenimine nanoformulations

Based on

1 Articles
2014 Most recent source

Composition

1

Tris-ethylenediaminetetraacetic acid buffer

Tris-EDTA buffer
Type Complex Compound
Formula
Role core
2

poly(lactic-co-glycolic acid)

PLGA
Type Polymer
Formula
Role layer
3

poly(iminoethylene)

polyethyleneimine polyaziridine PEI
Type Polymer
Formula
Role dopant
4

miR-150

Type Biomolecule
Formula
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release dependent on serum concentration

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human pancreatic cancer cell lines Colo-357

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(lactic-co-glycolic acid)
  • poly(iminoethylene)
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Product

miR-150-loaded poly (D,L-lactide-co-glycolide)/polyethylenimine nanoformulations

Diameter: ~ 183 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Product

miR-150-loaded poly (D,L-lactide-co-glycolide)/polyethylenimine nanoformulations

Hydrodynamic diameter: ~ 399 nm

Medium: water

Support: none

References

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