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shikonin-loaded acid-terminated (50:50) poly(D,L-lactide-co-glycolide) nanoparticle suspension

Based on

1 Articles
2014 Most recent source

Composition

1

acid-terminated (50:50) poly(D,L-lactide-co-glycolide)

poly(lactic-co-glycolic acid) PLGA
Type Polymer
Formula
Role raw materials
2

shikonin

SHK
Type Single Compound
Formula C16H16O5
Role loaded material
3

3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthene]-3-one

fluorescein free acid fluorescein dye fluorescein Flu dye Fluo FAM FSN
Type Single Compound
Formula C20H12O5
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
coefficient of determination dependent on kinetics model

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
human TEM1-negative endothelial MS1 cells

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Preparation

Method 1

Type: Physical formation
Source:
Product

shikonin-loaded acid-terminated (50:50) poly(D,L-lactide-co-glycolide) nanoparticle suspension

Hydrodynamic diameter: ~ 114 - ~ 495 nm

Medium: water

Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • shikonin
  • 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthene]-3-one
  • acid-terminated (50:50) poly(D,L-lactide-co-glycolide)
  1. XvhI3EMYjBoO4gL6d64cEzy
  2. oU32XUQxtHKTbMI3LGsIHA7644
Product

shikonin-loaded acid-terminated (50:50) poly(D,L-lactide-co-glycolide) nanoparticle suspension

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • shikonin
  • 3',6'-dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthene]-3-one
  • acid-terminated (50:50) poly(D,L-lactide-co-glycolide)
  1. uMaHe5PUhBuX4UdmcXiwRRVDOp
  2. hK8jU1hmbmdenlxI6M86uJhg2a7JE2G
Product

shikonin-loaded acid-terminated (50:50) poly(D,L-lactide-co-glycolide) nanoparticle suspension

Size: not specified

Medium/Support: none

References

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