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minocycline-loaded MPEG-PLGA nanoparticles

Based on

2 Articles
2016 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

methoxypolyethylene glycol-poly(DL-lactide) diblock copolymer nanoparticles

MPEG-PLA NP
Type Nano Material
Formula
Role carriers
2

minocycline

MIN
Type Single Compound
Formula C23H27N3O7
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug loading capacity

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Applications

Area Application Nanomaterial Variant Source
medicine/veterinary

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Characterization

Method Nanomaterial Variant Source
dynamic light scattering

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Biological effects

Biological system Test details Nanomaterial Variant Source
B6.129P-Cx3cr1tm1Litt/J mouse CD11b<sup>pos</sup>/CX3CR1<sup>low</sup>/Ly6C<sup>high</sup> macrophages M1

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • methoxypolyethylene glycol-poly(DL-lactide) diblock copolymer
  • minocycline
  1. ca4LN5Dgce78aOk
  2. 7bIteGtiLncDPL
  3. ydXdT
  4. uo8fQpr
Product

minocycline-loaded MPEG-PLGA nanoparticles

Size: 74 - 106 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  1. diH4XMFhNJHsL1HzJiyqEQgznn
Product

minocycline-loaded MPEG-PLGA nanoparticles

Size: not specified

Medium/Support: none

Method 3

Type: Physical formation
Source:
Product

minocycline-loaded MPEG-PLGA nanoparticles

Size: not specified

Medium: water

Support: none

References

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