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methotrexate-loaded Pluronic P105/F127 mixed micelles

Based on

1 Articles
2013 Most recent source

Composition

Image only illustrates the order and placement of components as described in literature.

1

Pluronic P105/Pluronic F127 mixture

Type Complex Compound
Formula
Role carriers
2

methotrexate

abitrexate folex MTX
Type Single Compound
Formula C20H22N8O5
Role loaded material

Properties

General physical and chemical properties

Property Value Source
drug release dependent on media pH

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Applications

Area Application Source
medicine/veterinary

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Characterization

Method Source
dynamic light scattering

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Biological effects

Biological system Test details Source
A-549 human lung adenocarcinoma cells

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Preparation

Method 1

Type: Physical formation
Source:
Starting materials
  • poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer
  • methotrexate
  1. xz2WXdVtdvGFDs1zj4S
  2. GKLS5i6uNTofKfQjSCV
Product

methotrexate-loaded Pluronic P105/F127 mixed micelles

Method 2

Type: Physical formation
Source:
Starting materials
  • poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer
  • methotrexate
  1. c1FoixiQ7NRvuWofLV4
  2. Yq3BUIQC6a5LDqkfZEz
Product

methotrexate-loaded Pluronic P105/F127 mixed micelles

Method 3

Type: Physical formation
Source:
Starting materials
  • poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer
  • methotrexate
  1. KuoIcAYm0NkHfSpajpm
  2. aBQvgLgJRBinT4kkijV
Product

methotrexate-loaded Pluronic P105/F127 mixed micelles

Method 4

Type: Physical formation
Source:
Starting materials
  • poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer
  • methotrexate
  1. 61F1iNtUrB6PpKQDEtc
  2. AwehOFvE5CqbbipY3iv
Product

methotrexate-loaded Pluronic P105/F127 mixed micelles

Method 5

Type: Physical formation
Source:
Starting materials
  • poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) block copolymer
  • methotrexate
  1. xWkRNhO3ltYwhriaAG2
  2. rjaBAjdFUkFsqzpIlre
Product

methotrexate-loaded Pluronic P105/F127 mixed micelles

References

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