Loading ...

Fast insight into nanotechnology

Access easily searchable nanoscience data, synthesis methods and literature

ITZ-loaded NLCs

Based on

1 Articles
2014 Most recent source

Composition

1

diethylene glycol monoethyl ether

2-(2-ethoxyethoxy)ethanol Transcutol® HP ethoxydiglycol Transcutol HP Transcutol P Transcutol Carbitol carbitol DEGMEE DGME
Type Single Compound
Formula C6H14O3
Role core
2

1,3-dioctadecanoylglycerol

glyceryl palmitostearate glycerol distearate Precirol ATO 5
Type Single Compound
Formula C39H76O5
Role fillers
3

polyoxyethylene (20) sorbitan monooleate

Polysorbate 80 Alkest TW 80 Tween 80
Type Polymer
Formula
Role layer
4

polyoxyl-15-hydroxystearate

Solutol®-HS15
Type Polymer
Formula
Role layer
5

cis-2-sec-butyl-4-[4-(4-{4-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4- ylmethoxy]phenyl}piperazin-1-yl)phenyl]-2,4-dihydro-1,2,4-triazol-3-one

itraconazole
Type Single Compound
Formula C35H38Cl2N8O4
Role loaded material

Properties

General physical and chemical properties

Property Value Nanomaterial Variant Source
drug release

More information/entries available to subscribers only.

Or, view sample content

Applications

Area Application Nanomaterial Variant Source
drug delivery

More information available to subscribers only.

Or, view sample content

Characterization

Method Nanomaterial Variant Source
differential scanning calorimetry

More information/entries available to subscribers only.

Or, view sample content

Biological effects

Biological system Test details Nanomaterial Variant Source
mouse

More information available to subscribers only.

Or, view sample content

Preparation

Method 1

Type: Physical formation
Source:
Product

ITZ-loaded NLCs

Diameter: 150 - 200 nm

Medium/Support: none

Method 2

Type: Physical formation
Source:
Starting materials
  • cis-2-sec-butyl-4-[4-(4-{4-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4- ylmethoxy]phenyl}piperazin-1-yl)phenyl]-2,4-dihydro-1,2,4-triazol-3-one
  • diethylene glycol monoethyl ether
  • 1,3-dioctadecanoylglycerol
  1. LbccETR
Product

ITZ-loaded NLCs

Diameter: 346.5 - 356.1 nm

Medium: water

Support: none

Method 3

Type: Physical formation
Source:
Starting materials
  • cis-2-sec-butyl-4-[4-(4-{4-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4- ylmethoxy]phenyl}piperazin-1-yl)phenyl]-2,4-dihydro-1,2,4-triazol-3-one
  • diethylene glycol monoethyl ether
  • 1,3-dioctadecanoylglycerol
  1. 00WSNkW
Product

ITZ-loaded NLCs

Diameter: 298.4 - 329.0 nm

Medium: water

Support: none

Method 4

Type: Physical formation
Source:
Starting materials
  • cis-2-sec-butyl-4-[4-(4-{4-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4- ylmethoxy]phenyl}piperazin-1-yl)phenyl]-2,4-dihydro-1,2,4-triazol-3-one
  • diethylene glycol monoethyl ether
  • 1,3-dioctadecanoylglycerol
  1. HKaMBqa
Product

ITZ-loaded NLCs

Diameter: 333.9 - 347.3 nm

Medium: water

Support: none

Method 5

Type: Physical formation
Source:
Starting materials
  • cis-2-sec-butyl-4-[4-(4-{4-[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4- ylmethoxy]phenyl}piperazin-1-yl)phenyl]-2,4-dihydro-1,2,4-triazol-3-one
  • diethylene glycol monoethyl ether
  • 1,3-dioctadecanoylglycerol
  1. E0MlDhw
Product

ITZ-loaded NLCs

Diameter: 374.9 - 453.3 nm

Medium: water

Support: none

References

Full content is available to subscribers only

To view content please choose from the following:

We use cookies to improve your experience with our site. More information

Sign up for a free trial